It is obvious from Table IIthat the inclusion of DCP into
niosomes composed of Tween 80 (F5–F8) led to a decrease in
the percentage entrapment efficiency of gentamicin. In
presence of DCP, equal molarity of this surfactant and
cholesterol illustrated lower entrapment efficiency than a
1:0.5 molar ratio. These results could be attributed to the
structure formed with Tween 80 which was not sufficiently
stabilized by DCP (33).