3.2. Comparison with an entire filtration run
In the second set of the experiments, two ten-capsule depth filters,
one in co-current and one in counter-current configuration,
were challenged with a mixture of homogenized yeast and whole
yeast at 300 LMH until a threshold pressure was attained, in order
to simulate a filtration run with a mammalian cell culture. In this
instance, we expect the depth filters to clog at different rates due
to the difference in fluxes and thus for their permeabilities to
change at different rates as well, which in turn changes the
pressure distribution within the multi-capsule depth filter.