By comparing the release data of gentamicin niosomes
containing DCP with that of DCP free-niosomes, it is clear
that the release is retarded in presence of DCP with Tween 60
and Brij 35. This confirms that DCP stabilizes the structure of
niosomal membrane and renders it less permeable. Whilst,
for niosomes prepared using Tween 80, the release is slower
from DCP free-niosomes. This may be attributed to the
structure of Tween 80 niosomal vesicles (33).