Middle East respiratory syndrome coronavirus (MERS-CoV) causes high fever, cough, acute respiratory tract infection and
multiorgan dysfunction that may eventually lead to the death of the infected individuals. MERS-CoV is thought to be
transmitted to humans through dromedary camels. The occurrence of the virus was first reported in the Middle East and it
subsequently spread to several parts of the world. Since 2012, about 1368 infections, including ~ 487 deaths, have been
reported worldwide. Notably, the recent human-to-human ‘superspreading’ of MERS-CoV in hospitals in South Korea has
raised a major global health concern. The fatality rate in MERS-CoV infection is four times higher compared with that of the
closely related severe acute respiratory syndrome coronavirus infection. Currently, no drug has been clinically approved to control
MERS-CoV infection. In this study, we highlight the potential drug targets that can be used to develop anti-MERS-CoV
therapeutics