The authors have also treated with Tabex 366 smokers with concomitant bronchitis and 239 patients treated with placebo. After completin the full treatment course (maximum duration 4 weeks), 55% of the patients gave up smoking, while in the group with placebo there was an effect in only 34%. Out of 230 smokers with chronic bronchitis (Berlin and Potsdam), treated with Tabex, 85% gave up smoking by the end of the 4th week, after 8 weeks - 66% and after 23 weeks - 46%. Almost all patients who had given up smoking manifested subjective improvement of the bronchitic symptoms.