These agreements significantly limit government ability to fulfil their population’s human right to health and life. Given the urgent need for increased access to essential patented medicines, there is no logical or patentable way to justify trading off the instrumental value of patent protection(to provide rewards and incentives for future innovation) at the present cost of the lives of millions of people. The CIPR report states this fact simply: “there are no circumstances in which the most fundamental human rights should be subordinated to the requirements of [IP] protection”. In any compulsory licensing and parallel importing in sub-Saharan Africa will likely have little impact on either corporate profits or incentives to innovate, since Africa accounts for just over 1 per cent of the global market. Moreover, the disease burden in developing regions (other than HIV/AIDS) is largely ignored in the development of new drugs, as the shocking disproportion of global health R&D expenditure on wealthy country illnesses illustrates: an estimated 90 per cent is spent on conditions affecting just 10 per cent of the world’s population, with priority conditional upon ability to pay.